Yuav Ua Li Cas Peb Tau Txais Quercetin Qib Siab?

Quercetin yog dab tsi?

Quercetin yog cov xim ntuj muaj nyob hauv ntau yam zaub, txiv hmab txiv ntoo thiab nplej.Quercetin 98% Extract hmoovyog ib qho ntawm cov antioxidants ntau tshaj plaws hauv kev noj haus thiab ua lub luag haujlwm zoo hauv kev pab koj lub cev tawm tsam dawb radical puas cuam tshuam nrog cov kab mob ntev. Tsis tas li ntawd, nws cov khoom antioxidant tuaj yeem pab txo qhov mob, cov tsos mob ua xua, thiab ntshav siab.

Quercetin compound yog cais raws li flavonol uas yog ib qho ntawm 6 subclasses ntawm flavonoid compounds. Lub npe tau siv txij li xyoo 1857 thiab tau muab los ntawm tsob ntoo ntoo. Quercetin (C15H10O7) yog ib qho aglycone tsis muaj suab thaj. Nws yog citron daj koob zoo li siv lead ua, tag nrho insoluble hauv dej txias, tsis yooj yim soluble hauv dej kub, tab sis yooj yim soluble hauv cawv thiab lipids. Quercetin glycoside yog tsim los ntawm kev txuas ib pawg glycosyl (ib qho qab zib xws li qabzib, rhamnose lossis rutinose) los hloov rau ib qho ntawm OH pawg (feem ntau nyob rau hauv 3 txoj haujlwm). Txuas nrog glycosyl pawg tuaj yeem hloov pauv solubility, nqus, thiab hauv vivo teebmeem.

Dab tsi yog quercetin nplua nuj zaub mov?

Quercetin flavonoid, feem ntau cov flavonoid molecules thiab yog dav faib nyob rau hauv cov nroj tsuag. Lawv muaj nyob rau hauv ntau yam khoom noj, xws li berries, txiv apples, brassica zaub, dos, txiv hmab txiv ntoo, txiv lws suav, shallots, tshuaj yej, nrog rau ntau yam noob, txiv ntseej, tawv ntoo, paj, thiab nplooj. Quercetin tseem muaj nyob hauv cov nroj tsuag tshuaj, suav nrog Hypericum perforatum, Ginkgo biloba, thiab Canadian elderberry. Hauv cov dos liab, qhov siab dua ntawm quercetin tau pom nyob rau hauv lub nplhaib sab nraud thiab nyob rau hauv qhov ze tshaj plaws rau cov hauv paus hniav, uas yog ib feem ntawm cov nroj tsuag nrog qhov siab tshaj plaws concentration. Ib txoj kev tshawb nrhiav pom tias txiv lws suav cog qoob loo muaj 79 feem pua ​​​​ntawm quercetin ntau dua li cov txiv hmab txiv ntoo cog qoob loo. Cov khoom noj ntawm quercetin muaj xws li zaub, txiv hmab txiv ntoo, txiv hmab txiv ntoo, txiv ntoo, dej haus, thiab lwm yam khoom siv cog qoob loo.

Yuav Ua Li Cas Peb Tau Txais Quercetin Qib Siab?

Tom qab mob siab rau kev tshawb fawb thiab ntau qhov kev txheeb xyuas, peb tau pom cov txheej txheem tsim khoom uas tuaj yeem tau txais cov khoom zoo quercetin nrog cov purity ntau dua 95 feem pua, uas yog tsim nyog rau cov khoom noj thiab tshuaj raw khoom.

Cov txheej txheem tsim muaj xws li cov hauv qab no: pub → hydrolysis → pom → ntxuav → refining. Cov kauj ruam tshwj xeeb yog raws li hauv qab no:

★ Pub: Sib tov inorganic muaj zog acid thiab dej kom tau cov kua qaub-dej sib tov, ntxiv rutin tom qab rhaub rau boiling;

Qhov twg, tus nqi noj rutin yog: txhua 1kg rutin ntxiv cov kua qaub-dej sib tov 7-15L; Qhov concentration ntawm hydrogen ion nyob rau hauv cov kua qaub-dej sib tov yog 0 4-lmol / L (zoo dua 0). 7-lmol/L). Cov inorganic muaj zog acid uas tuaj yeem siv tau yog hydrochloric acid lossis sulfuric acid. Txhawm rau kom ua tiav hydrolyze, cov kua yog khaws cia hauv qab nplawm.

★ Hydrolysis: Ua kom npau npau tsawg kawg 1 teev; nyiam ua kom boil rau 2 mus rau 3 teev kom tag nrho hydrolyze.

★Lim: Cov tshuaj hydrolyzed tau lim, thiab cov lim dej tau siv rau tom qab siv.

★ Ntxuav: Lub ncuav mog qab zib lim tau tom qab pom hauv 60-70 degree (zoo dua 70 degree) yog ntxuav nrog dej. Tsis txhob ntxuav kom txog thaum tus nqi pH ntawm eluate yog nruab nrab, ces qhuav kom tau quercetin crude lim ncuav mog qab zib. Nws yog ib qho yooj yim kom tshem tawm cov dej-soluble impurities nyob rau hauv kev tswj kub.

★ Kev kho kom zoo: Muab cov quercetin crude lim ncuav mog qab zib rau hauv 5 ~ 15 npaug ntawm cov tshuaj methanol refined. Do kom zoo, sawv ntsug thiab lim. Ua ntej, lub ncuav mog qab zib lim yog ntxuav nrog 2 ~ 10 npaug ntawm cov tshuaj methanol refined, thiab tom qab ntawd ntxuav nws nrog 5 mus rau 10 npaug ntawm cov dej ntshiab kom txog thaum nws tsis muaj xim thiab tsis muaj ntxhiab. Thaum kawg, qhuav kom tau cov khoom quercetin qib siab.

Qhov zoo ntawm cov txheej txheem ntau lawm yog raws li hauv qab no:

1. Ib puag ncig tus phooj ywg, tsis muaj tshuaj lom thiab muaj kuab paug tawm.

2. Yooj yim, tswj tau yooj yim, siab hloov pauv tus nqi, tuaj yeem txo tus nqi zoo heev.

3. Cov khoom tau txais muaj purity siab, thiab impurities thiab cov kab mob ua tau raws li cov qauv tsim.